Thursday, April 9, 2015

N Acetyl Cysteine: A Powerful Glutathione Precursor

Getting a NAC for Health                               A. Patrick Jonas, MD
Institute of Holistic Leadership        Presentation          April 9, 2015
1.       Introductions
2.       We covered some methylation issues before
3.       Tonight we’ll add some sulfation issues, especially N Acetyl Cysteine and Glutathione
4.       In the beginning, 60 trillion cells- each with 100,000 chemical reactions per minute
5.       Genomics ID 30,000 genes.  At OMIM.gov 20,000 single gene disorders, etc. etc. etc.
6.       Look at methylation sheet starting with leafy, green and yellow vegetables
7.       B’s to methylation to homocysteine to methionine to SAMe and back.
8.       If methyl toxic or homocysteine remains too high, CBS mutation may be operative
9.       See the confusing handout:  NAC comes to the rescue. Usual dose: 600mg twice daily
10.   N Acetyl L Cysteine, N Acetylcysteine, NAC -carries the amino acid L Cysteine.
11.   Precursor to Glutathione “The Mother of All Antioxidants”
12.   What happens then?  Let’s start low in the body and work up
13.   Connective tissue, immune system, autoimmune effects
14.   Ovaries –PCOS ovulation/pregnancy
15.   Liver- hangover cure, Tylenol toxicity and others, fatty liver, cholesterol, hepatitis, etc.
16.   Pancreas- Diabetes, Insulin Resistance, Weight
17.   Kidneys- IVP dye reactions
18.   Heart- increased blood flow, enhanced work outs, lower LDL Cholesterol, Lower Homocysteine
19.   Lungs- mucolytic in CF, CB, Flu
20.   Brain- “Brainitis” (All psychiatric diagnoses, all addiction diagnoses studied), chronic pain, cognitive impairment (see methylation page briefly), (Maybe gliaden addiction from wheat) CN & NA
21.   Infection, degeneration, malignancy, toxic, stroke, dental plaque, gambling, nail biting,
22.   Fibromyalgia
23.   Negative:  Cysteine kidney stones, nausea
24.   Etc.  NAC- WOW!
Questions?

Sunday, April 5, 2015

Interview with Therese Zink MD, MPH on the Dr Synonymous Show

Dr. Synonymous Interview with Therese Zink, MD, MPH Department Chair, WSUBSOM Family Medicine

Tuesday April 7 9:40PM  Click Here for Link to interview

Guiding Questions for direction:
1.        Congratulations, again for becoming Chair of Family Medicine at Wright State.  How long have you been on the job?

2.       How is it going?  What’s fun?  What’s challenging?  What’s surprising?

3.       What’s different compared to MN?
 
4.       How does a community based medical school keep focused on the mission these days?

5.       How is your writing going?  I really enjoyed The Country Doctor Revisited which we discussed on a show a couple years ago.  I have Confessions of a Sin Eater.  Would you explain the title to our listeners?

6.       Where is the department headed next?  What’s your vision/ plan?

7.       What do you notice in the WSU medical students that’s different/ similar to MN?

8.       How about our specialty?  What’s the future?  How are medical schools adjusting for the coming needs of society?

9     How’s your life away from the farm?  The cold of MN?

1   What else should our listeners know about you?  Your career?  Life?
Etc.

Tuesday, March 31, 2015

Family Medicine: Grieving and Crying With You

"Dr. Jonas, did you see this note yet?"   I look.  Someone died.  A patient of mine.  For 15 years. Gone.  Complex disease.  Complex life.  Complex grief.

Next patient.  Sinus pressure, sore throat, ear pain.

I read the death note again.  Sad. I see his face.  Reflect on our last encounter.
He was thankful.  He was prepared.

Next patient.  Hospital follow-up.  Review meds.  Change one dose.  Review the hospital labs.  Note the intentions of the surgeon.  Clarify preparations for the surgery and timing of follow-up.

Phone call with widow.  I listen to the story.  I respond to her feelings.  We agree a few times.
I hang up.  A wave of sadness comes over me.  A tear starts.  I stand to go to the next exam room.  A staff member asks me a question.  I have to clear my throat to answer.  One tear. One choke. One wave.  Until the next patient.

Look at his name.  Ask another staff if they saw that he died. Reflect again.  Part of doctoring. Intermittent grief.  Loss.  The human condition.  Ends for one.  Starts for another.

Next patient.  Can't get enough breath.  Medication, Ohio, COPD all fight the lungs.  Stop one drug. Start another.

Home.

Now I can cry with them.  For them.

Pray for them. And me.

The blog.  Not the next patient.

Peace.